Table 1.

Distribution of TP53 genotypes among CIN3+ cases versus women with persistent HPV infection and corresponding ORs and 95% CIs, adjusted for age

TP53 polymorphismGenotypeCIN3+ cases (n = 465)Persistent HPV controls (n = 379)OR*95% CI*Ptrend
rs17887200AA3973341.00.23
22369bp 3′ of STP A>GAG58431.20.781.9
GG20NA
rs9894946CC3963161.00.28
22342bp 3′ of STP T>CCT59600.760.511.1
TT431.20.255.6
rs1614984CC2492211.00.18
21226bp 3′ of STP C>TCT1751311.20.901.6
TT38271.30.742.2
rs12951053TT3212601.00.69
IVS7+92 T>GGT1331051.10.781.5
GG7120.490.191.3
rs12947788CC3212621.00.68
IVS7+72 T>CCT1371061.10.791.5
TT4110.340.111.1
rs1625895GG3482821.00.88
IVS6+62 A>GAG104900.960.691.3
AA1071.10.392.9
rs2909430AA3662921.00.42
IVS4-91 A>GAG85810.840.591.2
GG751.00.313.4
rs9895829TT4163331.00.60
IVS4-125 T>CCT30250.980.561.7
CC23NA
rs1042522 (Pro72Arg)GG2061821.00.29
Ex4+119 C>GCG1911441.20.911.7
CC61501.20.751.8
rs1642785GG2171661.00.66
IVS2+38 C>GCG1901670.880.651.2
CC51430.990.621.6
rs8079544GG4333551.00.67
IVS1-112 G>AAG30231.10.611.9
AA21NA
  • Abbreviation: NA, not applicable.

  • * Adjusted for age.

  • Numbers do not add up to totals because of missing values.