Table 1.

Study population characteristics

BRCA status*Age category (y)Breast cancer cases
Controls
Total
nMean (SD) agenMean (SD) age
BRCA1 carriers<508339.7 (6.2)9732.9 (9.1)180
>506262.8 (8.7)5460.8 (10.4)116
Total14548.9 (13.5)15142.9 (16.5)296
BRCA2 carriers<504141.1 (6.1)5735.2 (9.5)98
>503761.1 (8.8)4361.8 (11.4)80
Total7850.6 (12.5)10046.6 (16.8)178
Noncarriers<5011743.6 (5.0)9432.2 (5.0)211
>5061866.5 (10.3)58666.6 (10.3)1,204
Total73562.8 (12.8)68063.5 (12.5)1,415
  • * Ashkenazi founder mutations in BRCA1 (185delAG and 5382insC) and BRCA2 (6174delT).

  • Breast cancer combines breast cancer and breast/ovarian cancer cases.