Table 1.

Selected characteristics of incident, sporadic colorectal adenoma cases and controls; the Markers of Adenomatous Polyps II Study

Characteristic*n (cases/controls)Adenoma casesControlsP
Demographics
    Age (y.)46/4356.8 (7.7)55.7 (8.4)0.52
    Male (%)46/4354440.40
    White race (%)46/4296981.00
Family history
    First-degree relative with colorectal cancer (%)46/4317140.77
Lifestyle
    Physical activity (METs/d)44/4229.5 (23.5)27.1 (20.9)0.33
    BMI (kg/m2)46/4230.8 (7.3)30.4 (7.0)0.79
    Take aspirin at least once per week (%)46/4239381.00
    Take NSAID§ at least once per week (%)46/4235430.51
Smoking status (%)
    Never46/4241520.30
    Former4141
    Current187
Alcohol consumption (%)
    Never46/4211140.74
    Former2226
    Current6760
Dietary intakes
    Total energy (kcal/d)44/411,939.5 (780.0)1,509.2 (405.5)0.002
    Total fat (grams/d)44/4265.7 (16.5)65.8 (15.2)0.99
    Total dietary fiber (grams/d)44/4215.4 (5.7)15.4 (5.9)0.98
    Total calcium (mg/d)44/42882.7 (487.3)995.0 (505.4)0.24
    Total vitamin D (IU/d)44/42323.1 (289.9)373.4 (277.8)0.20
    Total folate (mcg/d)44/42480.2 (235.0)522.4 (266.3)0.44
  • * Continuous variables presented as mean (± SD), categorical variables as proportions in percent.

  • Based on t test for continuous variables, Fisher's exact test for dichotomous variables, and χ2 test for multilevel categorical variables.

  • Variables that were not normally distributed were normalized by natural log transformation.

  • § NSAID, not including aspirin.

  • Energy adjusted using residual method.

  • Total = diet + supplements.