Table 3.

Baseline concentrations of B vitamins and metabolites stratified by case-control status

AnalyteCases median (5th-95th percentile)Controls median (5th-95th percentile)P*
Betaine (μmol/L)32.7 (19.8-49.1)31.4 (19.5-49.0)0.18
Choline (μmol/L)10.4 (6.7-14.7)10.0 (6.8-14.4)0.07
Cysteine (μmol/L)277.5 (230.9-327.0)278.6 (232.6-328.7)0.16
MMA (μmol/L)0.150 (0.095-0.269)0.150 (0.104-0.274)0.002
Methionine (μmol/L)27.4 (21.0-35.1)27.3 (21.1-35.8)0.33
Vitamin B2 (Riboflavin; nmol/L)11.3 (4.4-40.5)10.3 (4.3-36.6)0.82
Vitamin B6 (pyridoxal phosphate) (nmol/L)36.5 (17.9-84.9)36.4 (18.2-84.8)0.13
  • * P values assessed by Wilcoxon signed rank test indicating the difference in concentrations between cases and controls.