Table 2.

Summary of the baseline characteristics for the average and high risk controls and cases

Healthy controls
Benign controls
Cases
Characteristic(n = 444)
(n = 124)
(n = 143)
Average-risk (n = 150)High-risk (n = 294)P*Average-risk (n = 110)High-Risk (n = 14)P*Average-risk (n = 102)High-risk (n = 41)P*
Age, median (range)52 (30-75)50 (31-83)0.0954 (27-83)51 (25-71)0.1458 (35-86)57 (19-80)0.83
BMI, median (range)24.5 (18.5-42.0)24.2 (16.2-43.9)0.8225.8 (18.8-51.6)26.6 (17.8-50.6)0.9225.6 (19.2-42.9)24.5 (20.6-53.7)0.90
Race
    White128 (85.3)269 (91.5)95 (86.4)13 (92.9)84 (82.4)37 (90.3)
    Asian3 (2.0)3 (1.0)4 (3.6)05 (4.9)1 (2.4)
    Black001 (0.9)001 (2.4)
    Other06 (2.0)3 (2.7)04 (3.9)0
    Unknown19 (12.7)16 (5.5)0.017 (6.4)1 (7.1)0.909 (8.8)2 (4.9)0.26
Menopause Status, n (%)
    Premenopause53 (35.3)96 (32.7)17 (15.5)3 (21.4)13 (12.7)2 (4.9)
    Postmenopause97 (64.6)198 (67.3)0.5793 (84.5)11 (78.6)0.5789 (87.3)39 (95.1)0.17
Hormone replacement therapy use (ever), n (%)
    No32 (21.3)178 (60.6)48 (43.6)6 (42.9)42 (41.2)14 (34.2)
    Yes45 (30.0)110 (37.4)53 (48.2)8 (57.1)47 (46.1)24 (58.5)
    Unknown73 (48.7)6 (2.0)<0.0019 (8.2)00.5113 (12.7)3 (7.3)0.36
  • Abbreviation: BMI, body mass index.

  • * P values were obtained by Wilcoxon rank-sum test for continuous variables and χ2 for categorical variables.

  • Other race includes American/Alaskan Indians and women who reported more than one race.