Table 2.

Geometric mean of PSA according to different characteristics

nGeometric mean of PSA (ng/mL)*Change in geometric mean (%)95% CI for change in geometric mean
PChange in geometric mean (%)95% CI for change in geometric mean
P
Lower limitUpper limitLower limitUpper limit
Indicators of diabetesAdjusted for ageAdditionally adjusted for BMI
Total = 766
DiabeticNo6360.84Reference groupReference group
Yes1300.70−16.8%−29.0%−2.4%0.024−14.6%−27.4%0.5%0.057
Duration of diabetes0-5 y340.59−29.6%−47.3%−5.9%0.018−28.0%−46.2%−3.8%0.027
6-10 y170.65−22.4%−48.3%16.4%0.220−22.4%−48.3%16.4%0.220
>10 y340.64−24.0%−43.2%1.6%0.063−22.2%−41.8%4.2%0.092
No duration reported450.883.9%−19.4%34.0%0.7699.7%−15.5%42.4%0.486
Diabetes medicationNo590.862.6%−18.0%28.4%0.8216.1%−15.4%33.0%0.610
Yes710.59−30.1%−43.1%−14.1%0.001−28.7%−42.1%−12.1%0.002
Insulin220.50−40.4%−58.3%−15.0%0.004−39.5%−57.7%−13.6%0.006
Oral medication510.63−25.3%−41.2%−5.2%0.017−23.6%−40.0%−2.6%0.030
HbA1cTotal = 771
Normal (<6.1%)5670.86Reference groupReference group
High (6.1-6.9%)1410.72−15.7%−27.9%−1.4%0.033−14.9%−27.3%−0.5%0.044
Very high (≥7%)630.60−30.2%−44.0%−13.0%0.001−28.8%−43.1%−10.9%0.003
BMIAdjusted for ageAdditionally adjusted for presence of diabetes
Total = 777
<251780.89Reference groupReference group
25-<304080.85−4.0%−17.4%11.4%0.589−3.5%−16.9%12.0%0.637
≥301910.76−14.6%−28.2%1.5%0.074−13.9%−27.8%2.7%0.096
AgeUnadjustedAdjusted for presence of diabetes and BMI
Total = 778
50-54 y470.86Reference groupReference group
55-59 y1021.0320.8%−10.1%62.1%0.20915.5%−14.1%55.3%0.340
60-64 y2081.1838.4%5.6%81.2%0.01837.5%4.9%80.2%0.021
65-69 y2271.3760.6%22.9%110.0%0.00157.4%20.4%105.8%0.001
70-74 y1941.6288.9%43.9%147.8%0.00088.7%43.7%147.8%0.000
  • Abbreviations: CI, confidence interval.

  • * Adjusted to age, 51 y.

  • All multivariate models included 765 persons, except for the model of HbA1c with 770 persons.

  • Intake of more than one drug possible, 23 used biguanides, 33 sulfonylureas, 7 α-glucosidase inhibitors, 1 another oral drug.