Table 1.

Demographic and clinical characteristics of cases and controls

VariableCases (n = 1,143)Controls (n = 1,097)P*
Age at diagnosis (cases) or study entry (controls) in y (±SD)65.5 (±10.7)65.6 (±10.8)0.79
    Age <60 y329 (29%)297 (27%)0.37
Male668 (58%)557 (51%)<0.001
Non-Hispanic whites1,143 (100%)1,097 (100%)
Ever-smoker682 (60%)505 (46%)
Smoking status<0.001
    Never-smoker455 (40%)592 (54%)
    Former smoker527 (47%)458 (42%)
    Current smoker148 (13%)41 (4%)
    Missing136
Years smoked (±SD)22.4 (±16.9)18.2 (±14.0)<0.001
Pack-years smoked (±SD)17.0 (±23.0)9.3 (±17.2)<0.001
BMI in kg/m2 (±SD)27.8 (±5.5)27.2 (±4.7)0.010
Region<0.001
    MN, IA, or WI (Tristate)579 (51%)748 (68%)
    North or South Dakota94 (8%)40 (4%)
    Other USA448 (39%)308 (28%)
    Other country22 (2%)1 (0%)
Diabetes mellitus (DM)<0.001
    No801 (70%)1,008 (92%)
    Yes342 (30%)89 (8%)
    DM (>2 y before pancreatic cancer dx)2240
Pancreas cancer stage at enrollment
    Resectable328 (29%)0
    Locally advanced379 (33%)0
    Metastatic430 (38%)0
    NOS6 (1%)0
Family history of pancreatic cancer (first-degree)79 (7%)43 (4%)0.002
  • Abbreviation: NOS, not otherwise specified.

  • * P unadjusted.

  • Only non-Hispanic whites included in the analysis.

  • Defined as <100 cigarettes in lifetime.