Table 5.

Distribution of menopausal status, BRCA1/2 mutation, and number of first-degree family members with breast and/or ovarian cancer for each of the three highest accruing sites

VariableStudy siteFrequency (%)P*
Menopausal status0.2917
    PreDuke21 (62)
OSU15 (71)
RPCI6 (100)
Overall42 (69)
    PeriDuke6 (18)
OSU5 (24)
RPCI0 (0)
Overall11 (18)
    PostDuke7 (21)
OSU1 (5)
RPCI0 (0)
Overall8 (13)
BRCA1/2 mutation0.1751
    NoDuke25 (74)
OSU19 (90)
RPCI6 (100)
Overall50 (82)
    YesDuke9 (26)
OSU2 (10)
RPCI0 (0)
Overall11 (18)
First-degree family members with breast/ovarian cancer0.0077
    ≤2 membersDuke31 (91)
OSU12 (57)
RPCI5 (83)
Overall48 (79)
    >2 membersDuke3 (9)
OSU9 (43)
RPCI1 (17)
Overall13 (21)
  • * Fisher's exact test.