Table 2.

Common ERBB2 alleles, haplotypes, and invasive breast cancer risk, Shanghai Breast Cancer Study, 1996 to 1998

Allele or haplotype
Cases, n (%)Controls, n (%)P
STR ASTR BSTR Crs2517951rs1136201
T (A1170 tag)678 (40.5)963 (39.7)0.601
G (V655)210 (12.5)304 (12.7)0.837
135897 (58.3)1270 (57.9)0.832
136205 (13.3)314 (14.3)0.396Overall χ2 = 6.8, P = 0.098
138416 (27.0)555 (25.3)0.256
346774 (52.2)1095 (51.9)0.826
34891 (6.1)124 (5.9)0.746Overall χ2 = 2.5, P = 0.661
350289 (19.5)394 (18.7)0.536
354131 (8.8)219 (10.4)0.139
113100 (6.4)149 (6.7)0.634
115114 (7.3)162 (7.3)0.922
11795 (6.0)116 (5.3)0.289
119102 (6.5)94 (4.3)0.002
121113 (7.2)166 (7.5)0.717
123131 (8.3)153 (6.9)0.111Overall χ2 = 17.1, P = 0.107
125143 (9.1)244 (11.0)0.054
127174 (11.1)249 (11.3)0.849
129156 (9.9)219 (9.9)0.983
131138 (8.8)194 (8.8)1.000
13392 (5.9)138 (6.2)0.620
TG205 (12.4)301 (13.0)0.723
TA468 (28.2)641 (27.1)0.455Overall χ2 = 3.3, P = 0.405
CA982 (59.2)1420 (60.1)0.576
136354TG90 (6.8)145 (7.8)0.333
138350TA232 (17.6)312 (16.7)0.516Overall χ2 = 1.3, P = 0.742
135346CA670 (50.8)949 (50.8)0.994
136354113TG29 (3.0)61 (5.0)0.074
135346115CA46 (5.4)51 (4.2)0.210
135346125CA47 (5.5)76 (6.2)0.491
135346127CA59 (6.9)84 (6.9)0.993Overall χ2 = 1.1, P = 0.911
135346129CA57 (6.6)79 (6.5)0.896
135346131CA50 (5.8)80 (6.6)0.488
135346133CA42 (4.9)62 (5.1)0.848