Table 1.

Selected characteristics of SCC cases by age at diagnosis

CharacteristicsAge 22-35 y (n = 165)
Age 36-53 y (n = 168)
Frequency* (%)Frequency (%)
Age (y)
    Mean (SD)31.0 (3.2)41.1 (4.0)
    Median3240
Birth year
    1951-195973 (44)120 (71)
    1960-196792 (56)48 (29)
Race
    White152 (92)143 (85)
    Non-White13 (8)25 (15)
Education
    High school or less74 (45)62 (37)
    More than high school91 (55)106 (63)
Income
    <$30,000/y93 (57)64 (39)
    ≥$30,000/y71 (43)100 (61)
    Unknown14
Marital status
    Never married27 (16)21 (13)
    Ever married138 (84)147 (88)
Cigarette smoking
    Never49 (30)74 (44)
    Former48 (29)33 (20)
    Current68 (41)61 (36)
Age at menses (y)
    <1232 (19)34 (20)
    12-1380 (48)94 (56)
    ≥1453 (32)40 (24)
Combined oral contraceptive use
    Never to <6 mo29 (18)52 (31)
    6 mo to <5 y57 (35)59 (35)
    ≥5 y79 (48)57 (34)
No. full-term pregnancies
    046 (28)30 (18)
    141 (25)30 (18)
    ≥278 (47)108 (64)
Full-term pregnancy rate
    None18 (11)15 (9)
    <1 per 10 y29 (18)57 (34)
    1 per 10 to <2 per 10 y55 (34)61 (37)
    2 per ≥10 y62 (38)34 (20)
Pap frequency in most recent decade
    None7 (4)2 (1)
    1-5 per decade67 (41)102 (63)
    6-8 per decade10 (6)15 (9)
    1/y61 (37)34 (21)
    >1/y19 (12)10 (6)
    Unknown15
Lifetime no. sex partners
    15 (3)11 (7)
    2-446 (28)52 (31)
    5-1474 (45)69 (41)
    ≥1540 (24)35 (21)
    Unknown01
C. trachomatis serology
    Negative45 (52)26 (58)
    Positive41 (48)19 (42)
    Test not done or unknown79123
Herpes simplex virus type 2 serology§
    Negative79 (56)34 (47)
    Positive61 (44)39 (53)
    Test not done or unknown2595
International Federation of Gynecology and Obstetrics stage
    I151 (92)131 (81)
    II-IV13 (8)30 (19)
    Unknown17
HPV DNA results
    HPV negative14 (11)9 (9)
    HPV-16 positive88 (71)60 (62)
    HPV-18 positive8 (6)10 (10)
    HPV-16 and HPV-18 positive6 (5)9 (9)
    HPV positive for other types§8 (6)9 (9)
    HPV positive, type unknown30
    Insufficient sample83
    Test not done or unknown3068
HPV-16/HPV-18 serology
    HPV-16 and HPV-18 negative80 (56)30 (42)
    Only HPV-16 positive29 (20)14 (19)
    Only HPV-18 positive13 (9)16 (22)
    HPV-16 and HPV-18 positive20 (14)12 (17)
    Test not done or unknown2396
  • * Unless otherwise indicated.

  • Includes currently or formerly married or lived with a partner for >6 mo.

  • C. trachomatis, herpes simplex virus type 2, HPV-16, and HPV-18 serology only available on cases enrolled before 1999, which excludes 94 cases (88 diagnosed at ages 36-53 y and 8 diagnosed at ages 22-36 y).

  • § Includes HPV types 6, 31, 33, 45, 53, 58, and/or 73.