Table 1.

Risk factors for pancreatic cancer mortality in the original Whitehall Study (N = 17,898)

No. deaths/no. menRate ratio (95% confidence intervals)
Age-adjustedMultiple adjustment*
Body mass index (kg/m2)
    Tertile 153/5,9691.01.0
    Tertile 254/5,9940.98 (0.67-1.43)1.02 (0.69-1.50)
    Tertile 356/5,9351.10 (0.75-1.60)1.18 (0.79-1.75)
    Per 1 SD (2.98 kg/m2) increase1.01 (0.86-1.18)1.03 (0.87-1.23)
Plasma cholesterol (mmol/L)
    Tertile 156/6,1241.01.0
    Tertile 269/5,7331.32 (0.93-1.88)1.32 (0.93-1.88)
    Tertile 338/6,0410.71 (0.47-1.07)0.73 (0.48-1.10)
    Per 1 SD (1.21 mmol/L) increase0.91 (0.78-1.07)0.92 (0.78-1.08)
Diastolic blood pressure (mmHg)
    Tertile 163/5,6871.01.0
    Tertile 250/6,2190.75 (0.52-1.09)0.75 (0.52-1.10)
    Tertile 350/5,9910.88 (0.61-1.28)0.89 (0.60-1.31)
    Per 1 SD (13.8 mmHg) increase0.93 (0.78-1.09)0.92 (0.77-1.10)
Systolic blood pressure (mmHg)
    Tertile 159/5,8701.01.0
    Tertile 257/6,0420.97 (0.67-1.39)0.96 (0.67-1.39)
    Tertile 347/5,9860.92 (0.63-1.36)0.93 (0.62-1.38)
    Per 1 SD (21.2 mmHg) increase0.98 (0.83-1.15)0.98 (0.83-1.17)
Physical activity
    High33/2,9551.01.0
    Moderate78/9,3390.93 (0.66-1.33)0.92 (0.65-1.30)
    Sedentary52/5,6041.37 (0.89-2.12)1.32 (0.84-2.06)
Socioeconomic position
    Administrative (highest socioeconomic status)13/9081.43 (0.80-2.54)1.43 (0.80-2.55)
    Professional/executive106/11,6521.01.0
    Clerical21/2,8230.95 (0.59-1.51)1.00 (0.62-1.63)
    Other (lowest socioeconomic status)16/1,6781.29 (0.76-2.18)1.29 (0.74-2.25)
    BC and DS7/8370.94 (0.44-2.02)0.99 (0.46-2.13)
  • * Excluding the predictor variable of interest, multiple adjustment is adjustment for body mass index, plasma cholesterol, physical activity, socioeconomic status, diabetes/blood glucose, marital status, forced expiratory volume in 1 s, height, age at risk, smoking, and diastolic and systolic blood pressure (estimates for components of blood pressure are not mutually adjusted).

  • British Council and Diplomatic Service included as separate categories because grade levels are not comparable with other civil service departments.