Table 1.

Clinical characteristics by tertiles of p63 percent-positive area of men diagnosed with prostate cancer in PHS, 1983-2007

CharacteristicsTertiles of p63 percent positivity
P
1 (0-1.76)
2 (1.77-3.89)
3 (3.90-53.79)
(n = 99)
(n = 100)
(n = 99)
Mean (SE) or %
Median (interquartile range) p63 percent positivity1.1 (0.8-1.4)2.5 (2.0-3.0)6.6 (4.9-9.1)
Age at diagnosis (y)65.8 (0.6)67.2 (0.6)65.9 (0.6)0.83*
Body mass index (baseline; kg/m2)24.6 (0.3)24.4 (0.3)24.6 (0.3)0.99*
Follow-up time (y)10.0 (0.4)9.7 (0.4)8.0 (0.4)<0.001*
PSA at diagnosis (ng/mL)11.2 (3.4)7.4 (3.6)14.8 (3.6)0.49*
Missing (%)7.117.017.2
Gleason score
    4-629 (29.3)23 (23.0)38 (38.4)0.05
    757 (57.6)61 (61.0)41 (41.4)
    8-1013 (13.1)16 (16.0)20 (20.2)
Clinical stage
    T1, NX/N045 (45.5)47 (47.0)58 (58.6)0.15
    T2, NX/N047 (47.5)45 (45.0)33 (33.3)
    T3/T4 or N1/M14 (4.0)4 (4.0)1 (1.0)
    Missing (%)3.04.07.1
Prostate cancer death
    Yes2 (2.0)8 (8.0)9 (9.1)0.04§
    No97 (98.0)92 (92.0)90 (90.9)
  • * F test for trend.

  • Forty-nine percent of men with missing PSA (n = 20) were diagnosed in pre-PSA era.

  • Global χ2 test.

  • § χ2 test for trend across tertiles.