Table 1.

HRs for total cancer and specifically, for cancer of the colon, lung, breast, and prostate, by categories of thyrotropin measured at baseline

Thyrotropin (mU/L)Persons (n)Cancers (n)HR*HR (95% CI)
Total cancer
    <0.50674761.361.34 (1.06-1.69)
    0.50-1.412,3891,0101.0 (Reference)1.0 (Reference)
    1.5-2.410,8829140.950.98 (0.90-1.08)
    2.5-3.53,5973130.890.95 (0.83-1.08)
    >3.52,1491980.900.96 (0.82-1.12)
Colon cancer
    <0.5067491.421.38 (0.70-2.73)
    0.50-1.412,3891061.0 (Reference)1.0 (Reference)
    1.5-2.410,8821191.151.18 (0.90-1.53)
    2.5-3.53,597461.181.23 (0.86-1.74)
    >3.52,149230.910.95 (0.60-1.50)
Lung cancer
    <0.50674112.602.34 (1.24-4.40)
    0.50-1.412,389841.0 (Reference)1.0 (Reference)
    1.5-2.410,882640.810.99 (0.71-1.37)
    2.5-3.53,597240.871.25 (0.79-1.98)
    >3.52,14990.540.87 (0.43-1.74)
Breast cancer
    <0.50503121.201.20 (0.67-2.16)
    0.50-1.48,0271641.0 (Reference)1.0 (Reference)
    1.5-2.47,1181180.790.78 (0.61-0.99)
    2.5-3.52,476460.860.85 (0.61-1.18)
    >3.51,586300.860.85 (0.57-1.25)
Prostate cancer
    <0.50171101.961.97 (1.04-3.76)
    0.50-1.44,3621351.0 (Reference)1.0 (Reference)
    1.5-2.43,7641210.940.93 (0.73-1.20)
    2.5-3.51,121370.790.78 (0.54-1.13)
    >3.5563230.870.86 (0.55-1.35)
  • * HRs adjusted for age and sex.

  • HRs adjusted for age, sex, and smoking status.