Table 4.

Risk of breast cancer recurrence, breast cancer mortality and all-cause mortality associated with physical activity

Recurrence (n = 225)
Breast cancer mortality (n = 102)
All-cause mortality (n = 187)
Model I*
Model II
Model I*
Model II
Model I*
Model II§
HR (95% CI)HR (95% CI)HR (95% CI)HR (95% CI)HR (95% CI)HR (95% CI)
Total activity, MET-h/wk
    Q1 (<29)RefRefRefRefRefRef
    Q2 (29-<44)0.65 (0.44-0.97)0.76 (0.51-1.13)0.83 (0.49-1.40)1.01 (0.57-1.78)0.70 (0.47-1.04)0.89 (0.59-1.33)
    Q3 (44-<62)0.82 (0.57-1.19)0.87 (0.59-1.29)0.71 (0.41-1.24)0.70 (0.38-1.29)0.67 (0.45-1.00)0.82 (0.54-1.25)
    Q4 (≥62)0.79 (0.54-1.15)0.91 (0.61-1.36)0.68 (0.39-1.18)0.87 (0.48-1.59)0.58 (0.38-0.88)0.76 (0.48-1.19)
    P for trend0.400.780.140.410.010.20
Moderate-vigorous activity, MET-h/wk
    Q1 (<5.3)RefRefRefRefRefRef
    Q2 (5.3-<15)0.67 (0.46-0.97)0.73 (0.49-1.09)0.68 (0.41-1.15)0.77 (0.44-1.34)0.63 (0.43-0.93)0.71 (0.48-1.07)
    Q3 (15-<27)0.62 (0.42-0.91)0.75 (0.50-1.12)0.47 (0.26-0.85)0.47 (0.24-0.91)0.49 (0.32-0.74)0.58 (0.37-0.90)
    Q4 (≥27)0.84 (0.59-1.20)1.00 (0.68-1.46)0.68 (0.41-1.15)0.90 (0.51-1.58)0.56 (0.38-0.83)0.74 (0.49-1.13)
    P for trend0.310.950.070.380.0010.06
H/wk of moderate activity
    <1RefRefRefRefRefRef
    1-<30.76 (0.53-1.09)0.81 (0.55-1.18)0.51 (0.29-0.89)0.65 (0.36-1.16)0.59 (0.40-0.87)0.71 (0.48-1.06)
    3-<60.80 (0.56-1.13)0.86 (0.60-1.25)0.69 (0.42-1.13)0.69 (0.40-1.19)0.57 (0.39-0.84)0.66 (0.44-1.00)
    ≥60.66 (0.44-0.97)0.81 (0.54-1.22)0.56 (0.32-0.98)0.73 (0.40-1.33)0.51 (0.34-0.79)0.66 (0.42-1.03)
    P for trend0.050.360.070.260.0010.04
Hours/wk of vigorous activity
    0RefRefRefRefRefRef
    >0-<10.88 (0.61-1.28)0.91 (0.62-1.36)0.72 (0.40-1.28)0.79 (0.42-1.48)0.74 (0.48-1.15)0.90 (0.57-1.41)
    ≥11.06 (0.78-1.44)1.12 (0.81-1.56)0.85 (0.53-1.36)1.10 (0.68-1.80)0.87 (0.61-1.23)1.02 (0.70-1.47)
    P for trend0.800.580.400.820.331.0
Selected activities, MET-h/wk
    <9RefRefRefRefRefRef
    ≥91.00 (0.76-1.31)1.16 (0.87-1.55)0.91 (0.61-1.36)1.19 (0.78-1.84)0.78 (0.57-1.06)0.98 (0.71-1.35)
  • HR, hazard ratio; 95% CI, 95% confidence interval.

  • * Adjusted for age.

  • Adjusted for age, number of positive nodes, stage and weight at 18 y.

  • Adjusted for age, number of positive nodes, stage, weight at 18 y, type of treatment (chemotherapy/radiation) and type of surgery (mastectomy or conserving).

  • § Adjusted for age, number of positive nodes, stage, weight at 18 y, education level and smoking status.