Case* (n = 29) | Control* (n = 31) | Prop diff (%)^{†} | P_{diff}^{‡} | Odds ratio^{§} (95% CI) | Model covariates^{∥} |
---|---|---|---|---|---|

1.10 (0.14) | 0.80 (0.14) | 37.5 | 0.14 | 2.26 (0.91-5.64) | NSAID use |

1.22 (0.14) | 0.74 (0.14) | 64.9 | 0.02 | 2.83 (1.11-7.24) | Total energy intake |

1.41 (0.17) | 0.88 (0.15) | 60.2 | 0.01 | 3.00 (1.17-7.70) | Family history of CRC |

1.39 (0.16) | 0.84 (0.15) | 65.5 | 0.01 | 3.75 (1.18-11.98) | NSAID use, energy, family history of CRC |

NOTE: Adjusted for risk factors or potential confounders (Table 1, Table 3). Batch standardized as individual value divided by batch mean; full crypt values.

↵* Mean staining densities and SEs.

↵† Difference between means (cases - controls) divided by mean in controls × 100%.

↵‡ Difference

*P*value for comparison of means (analysis of covariance).↵§ Association between TGF-α expression (as a continuous variable) and adenoma (relative odds of being a case).

↵∥ All estimates adjusted for age and sex and other covariates as specified; total energy intake modeled as a continuous variable.