Table 1.

Individual and averaged values of urinary NNAL half-life

Monitoring time (d)Two-compartmental model half-lifeNoncompartmental model half-life
Alpha phase (h)Terminal (beta) phase (d)Terminal phase (d)
Clinical settings
    Subject A1412.411.910.5
    Subject B1410.29.37.0
    Subject C1412.011.314.8
    Subject D1419.69.96.4
    Subject E1410.29.38.8
    Subject F1411.37.96.9
    Subject G1411.710.79.6
    Subject H1426.612.29.2
    Average1414.310.39.1
    SD (CV%)5.8 (41)1.5 (14)2.7 (30)
Real-life settings
    Subject I3530.720.616.9
    Subject J4224.015.612.0
    Subject K28127.1*7,011.2*12.7
    Subject L5645.922.921.8
    Subject M1425.211.413.3
    Subject M25611.911.119.1
    Subject M35614.511.716.8
    Average4527.817.616.0
SD (CV%)11.3 (25)14.7 (53)5.1 (29)3.9 (24)
  • *Data excluded from statistical analysis.