Table 3.

Correlation of variables by exposure type associated with gene-specific promoter methylation

VariablesAPCCCND2GSTP1MGMTRARβ2P16
P2)*P2)P2)P2)P2)P2)
Age0.5440.8220.1810.9210.7150.616
Nonsmoking0.7220.0530.6650.8890.3060.921
Income (>$50,000)0.1870.0110.5670.060.0680.507
Family cancer history0.2030.8840.0540.4540.6730.846
Diet and nutrition (high fat)0.8190.9980.2490.6450.0070.814
CO (<6 ppm)0.6210.5420.0420.5530.5290.132
Environmental tobacco smoke0.3150.3530.3680.0430.250.007
Nonalcohol0.1250.0160.430.3210.0880.367
Diabetes0.0410.8140.6850.7150.0340.639

NOTE: Referent group for each variable: age 1 (40-49) and 2 (50 and 90); current smokers; $0 to $49,999; no cancer in family; low fat; ≥6 ppm; no environmental tobacco smoke exposure; current alcohol; no diabetes.

  • *P ≤ 0.05 was considered statistically significant.