Table 2.

Relationship of skin damage score to pigmentary traits and sun sensitivity

n (%)Unadjusted OR (95% CI)AOR* (95% CI)
Natural skin color
    Dark/olive41 (8.0)1.00 (reference)1.00 (reference)
    Olive/medium110 (21.4)2.34 (1.22-4.50)3.62 (1.82-7.21)
    Medium/fair180 (35.0)4.00 (2.14-7.50)6.09 (3.14-11.80)
    Fair183 (35.6)2.91 (1.56-5.44)4.51 (2.33-8.75)
Ptrend = 0.005Ptrend < 0.001
Hair color
    Black29 (5.6)1.00 (reference)1.00 (reference)
    Dark brown195 (37.9)1.77 (0.85-3.69)2.88 (1.36-6.09)
    Blonde262 (51.0)2.08 (1.01-4.29)3.88 (1.85-8.16)
    Red28 (5.5)5.05 (1.89-13.46)11.31 (4.08-31.36)
Ptrend = 0.003Ptrend < 0.001
Eye color
    Brown115 (22.4)1.00 (reference)1.00 (reference)
    Hazel91 (17.7)1.65 (1.01-2.69)1.75 (1.06-2.91)
    Green66 (12.8)1.10 (0.64-1.88)1.42 (0.82-2.45)
    Blue/gray242 (47.1)1.49 (1.01-2.20)1.72 (1.14-2.59)
Ptrend = 0.13Ptrend = 0.03
Teen freckling
    No freckles132 (25.6)1.00 (reference)1.00 (reference)
    Few freckles219 (42.5)1.59 (1.08-2.34)1.99 (1.33-2.98)
    Some freckles108 (21.0)1.98 (1.26-3.12)3.05 (1.89-4.94)
    Many freckles56 (10.9)3.89 (2.20-6.90)6.89 (3.70-12.83)
Ptrend < 0.001Ptrend < 0.001
Upper inner arm melanin density (per 1% increase)n = 504 (range, -8.79 to 8.04)0.89 (0.79-1.01)0.81 (0.72-0.92)
P = 0.06P = 0.001
Buttock melanin density (per 1% increase)n = 504 (range, -6.93 to 5.47)0.78 (0.69-0.87)0.72 (0.64-0.82)
P < 0.001P < 0.001
Reaction to first exposure to midday summer sun
    Never burn20 (3.9)1.00 (reference)1.00 (reference)
    Burn after >2 h64 (12.4)0.95 (0.39-2.31)1.61 (0.61-4.26)
    Burn after 1-2 h137 (26.6)1.17 (0.51-2.68)2.61 (1.05-6.52)
    Burn after 0.5-1 h144 (28.0)1.61 (0.70-3.68)3.42 (1.37-8.54)
    Burn after <0.5 h150 (29.1)1.35 (0.59-3.07)3.15 (1.26-7.89)
Ptrend = 0.11Ptrend = 0.003
Reaction to 1 h of summer sun
    Burn then peel203 (39.5)1.00 (reference)1.00 (reference)
    Burn then tan209 (40.7)0.84 (0.60-1.19)0.78 (0.54-1.11)
    Tan only102 (19.8)0.65 (0.43-0.99)0.43 (0.27-0.67)
Ptrend = 0.05Ptrend < 0.001
End of summer tan
    Dark98 (19.1)1.00 (reference)1.00 (reference)
    Medium212 (41.3)1.60 (1.03-2.47)1.69 (1.07-2.66)
    Light136 (26.5)1.52 (0.95-2.44)1.91 (1.15-3.15)
    No tan68 (13.2)1.65 (0.94-2.90)2.65 (1.46-4.82)
Ptrend = 0.13Ptrend = 0.002
Past history of blistering sunburn
    No172 (33.7)1.00 (reference)1.00 (reference)
    Yes338 (66.3)2.17 (1.56-2.31)1.97 (1.40-2.78)
P < 0.001P < 0.001
Number of sunburns in lifetime
    Never69 (13.4)1.00 (reference)1.00 (reference)
    Once88 (17.1)0.72 (0.41-1.26)0.75 (0.42-1.35)
    2-5 times223 (43.3)1.26 (0.78-2.02)1.36 (0.82-2.25)
    6-10 times69 (13.4)1.39 (0.77-2.51)1.49 (0.80-2.77)
    >10 times66 (12.8)2.53 (1.39-4.61)2.86 (1.50-5.43)
P < 0.001P < 0.001
  • *Adjusted for left/right cast, age, sex, and cumulative UVR dose; see text for model details.

  • By nurse observation.

  • By self-report.