Table 4.

ICCs (95% confidence intervals) for individual and grouped EM, expressed as absolute concentrations, percent of total EM, and selected EM ratios

AnalyteICC (95% confidence interval)
Absolute concentration% of total EM
Parent EM0.52 (0.41-0.62)0.64 (0.54-0.72)
    Estrone0.52 (0.42-0.63)0.67 (0.58-0.75)
    Estradiol0.49 (0.39-0.60)0.52 (0.42-0.62)
Catechol EM0.72 (0.64-0.79)0.85 (0.80-0.89)
2-Catechol EM0.72 (0.64-0.78)0.84 (0.79-0.88)
    2-Hydroxyestrone0.71 (0.63-0.78)0.83 (0.78-0.87)
    2-Hydroxyestradiol0.67 (0.59-0.75)0.68 (0.60-0.76)
4-Catechol EM
    4-Hydroxyestrone0.58 (0.48-0.67)0.51 (0.41-0.62)
Methylated catechol EM0.61 (0.51-0.69)0.64 (0.55-0.73)
Methylated 2-catechol EM0.62 (0.52-0.70)0.65 (0.56-0.73)
    2-Methoxyestrone0.62 (0.52-0.71)0.67 (0.59-0.75)
    2-Methoxyestradiol0.51 (0.41-0.62)0.53 (0.42-0.63)
    2-Hydroxyestrone-3-methyl ether0.51 (0.40-0.61)0.50 (0.40-0.61)
Methylated 4-catechol EM0.25 (0.15-0.39)0.27 (0.17-0.40)
    4-Methoxyestrone0.27 (0.17-0.41)0.30 (0.20-0.43)
    4-Methoxyestradiol0.14 (0.06-0.30)0.13 (0.05-0.29)
2-Pathway EM 0.72 (0.64-0.78)0.85 (0.80-0.89)
4-Pathway EM0.57 (0.47-0.67)0.51 (0.40-0.61)
16-Pathway EM0.52 (0.41-0.62)0.82 (0.76-0.86)
    16α-Hydroxyestrone0.46 (0.35-0.57)0.64 (0.55-0.72)
    Estriol0.54 (0.44-0.64)0.77 (0.70-0.83)
    17-Epiestriol0.50 (0.39-0.60)0.56 (0.46-0.65)
    16-Ketoestradiol0.42 (0.31-0.53)0.59 (0.49-0.68)
    16-Epiestriol0.45 (0.34-0.56)0.56 (0.46-0.66)
Total EM0.39 (0.28-0.51)
EM ratios
4-Catechol/2-catechols0.21 (0.11-0.35)
2-Catechols/16-pathway0.83 (0.78-0.88)
Catechols/16-pathway0.83 (0.77-0.87)
4-Pathway/2-pathway0.21 (0.11-0.35)
2-Pathway/16-pathway0.83 (0.77-0.87)
4-Pathway/16-pathway0.70 (0.62-0.77)
2,4-Pathway/16-pathway0.85 (0.80-0.89)
2-Pathway/4,16-pathway0.84 (0.79-0.88)
2-Catechols/methylated 2-catechols0.58 (0.48-0.67)
4-Catechol/methylated 4-catechols0.42 (0.31-0.54)
Catechols/methylated catechols0.60 (0.50-0.69)
Parent estrogens/estrogen metabolites0.65 (0.55-0.73)