Table 2.

Selected baseline and disease characteristics and multivariable relative risks with 95% confidence intervals for the association between the characteristics and death by cause among women diagnosed with invasive breast cancer from 1995-2004 in the California Teachers Study

Total (n = 3,539) Breast cancer deaths (n = 221)RR* (95% CI)All causes of death (n = 460)RR* (95% CI)
Age (years)
    Mean (SD)58.9 (11.75)----
    Range26-94
n (%)n (%)n (%)
Race/ethnicity
    White3,173 (89.7)199 (90.0)1.00417 (90.7)1.00
    Non-white366 (10.3)22 (10.0)0.87 (0.55-1.39)43 (9.3)1.02 (0.74-1.43)
BMI (kg/m2)
    <251,945 (55.0)99 (44.8)1.00220 (47.8)1.00
    25-29973 (27.5)61 (27.6)1.16 (0.83-1.62)119 (25.9)0.98 (0.78-1.24)
    ≥30469 (13.2)39 (17.6)1.71 (1.16-2.53)72 (15.7)1.42 (1.08-1.88)
    Unknown152 (4.3)22 (10.0)2.51 (1.51-4.15)49 (10.7)1.61 (1.14-2.27)
Total caloric intake (kcal)
    <1,2711,061 (30.0)78 (35.3)1.00160 (34.8)1.00
    1,271-1,6821,047 (29.6)49 (22.2)0.67 (0.46-0.97)121 (26.3)0.85 (0.67-1.09)
    >1,6821,102 (31.1)68 (30.8)0.79 (0.56-1.11)111 (24.1)0.75 (0.58-0.97)
    Unknown329 (9.3)26 (11.8)1.01 (0.63-1.64)68 (14.9)1.06 (0.78-1.44)
Estrogen receptor status
    Positive2,549 (72.0)122 (55.2)1.00300 (65.2)1.00
    Negative450 (12.7)59 (26.7)2.88 (2.08-3.99)80 (17.4)1.71 (1.32-2.22)
    Unknown540 (15.3)40 (18.1)1.38 (0.94-2.03)80 (17.4)1.05 (0.80-1.38)
Number of comorbid conditions
    02,670 (75.4)162 (73.3)1.00281 (61.1)1.00
    1755 (21.3)45 (20.4)0.82 (0.58-1.16)143 (31.1)1.29 (1.04-1.60)
    ≥2114 (3.2)14 (6.3)1.46 (0.81-2.64)36 (7.8)1.72 (1.18-2.50)
Disease stage§
    Localized2,437 (68.9)65 (29.4)1.00244 (53.0)1.00
    Nonlocalized1,074 (30.3)153 (69.2)5.75 (4.24-7.78)206 (44.8)2.67 (2.19-3.25)
    Unknown28 (0.8)3 (1.4)3.28 (0.97-11.11)10 (2.2)2.37 (1.14-4.93)

NOTE: All assessments were completed at baseline.

  • *All models are stratified by age (in years) and adjusted for race, BMI, total caloric intake, estrogen receptor status, number of comorbid conditions, stage and physical activity summary variable.

  • Includes breast cancer and other causes of death: cancers other than breast cancer (69), cardiovascular disease (68), cerebrovascular disease (38), thrombosis (3), cardiopulmonary and pulmonary diseases (28), diabetes (4), and other (29).

  • Based on self-reported personal history of stroke, heart attack/myocardial infarction, diabetes and high blood pressure.

  • §Nonlocalized includes regional and metastatic disease.