Table 1.

Origin and classification of the entire sample collection

CenterNo. of tissue blocksNo. of subjects per diagnostic class
Neg/neg (1)Neg/pos (2)Pos (3)Total
UTHSC*4636491155
UCHSC415452368
UMaas3655526116197
Comm§2193030
Total1,462164170116450

NOTE: The samples belonged to three different histopathologic classes: (1) neg/neg, two negative biopsies at least 24 mo apart (if three consecutive negative biopsies were recorded, no time limit was required); (2) neg/pos, samples with a first negative biopsy followed by a positive biopsy <24 mo later; (3) pos, samples from patients diagnosed with prostate cancer in the tested biopsy series.

  • *Dean Troyer, M.D., University of Texas Health Science Center at San Antonio, TX.

  • Scott Lucia, M.D., University of Colorado Health Science Center, Denver, CO.

  • Adriaan de Bruïne, M.D., University of Maastricht, Maastricht, the Netherlands.

  • §U.S. commercial tissue repository.