Table 3.

wSMRs and 95% CI for all and cancer-specific cause of death by family characteristics

Cause of deathFamily historyYoungest age at onsetFamily history score tertile
Sporadic kindredsFamilial kindreds<50 y≥50 yLowMediumHigh
All cause0.86 (0.81-0.91)0.86 (0.81-0.91)1.00 (0.90-1.11)0.84 (0.8-0.88)0.71 (0.66-0.76)0.87 (0.81-0.93)1.16 (1.08-1.25)
Extrapancreatic cancers1.55 (1.39-1.73)1.41 (1.26-1.58)1.52 (1.23-1.85)1.47 (1.35-1.61)1.27 (1.11-1.44)1.38 (1.2-1.58)2.03 (1.77-2.33)
Breast1.06 (0.66-1.62)1.66 (1.15-2.34)1.98 (1.01-3.52)1.26 (0.91-1.71)1.16 (0.69-1.81)0.95 (0.51-1.62)2.22 (1.42-3.33)
Ovarian1.28 (0.58-2.48)2.05 (1.10-3.49)2.75 (0.88-6.52)1.50 (0.87-2.4)1.24 (0.49-2.6)2.14 (1.01-4.00)1.73 (0.63-3.83)
Colon1.19 (0.81-1.70)1.33 (0.93-1.86)2.31 (1.30-3.81)1.13 (0.84-1.5)1.04 (0.67-1.54)1.00 (0.59-1.58)2.15 (1.38-3.19)
Melanoma1.65 (0.60-3.65)1.65 (0.6-3.65)1.93 (0.23-7.07)1.58 (0.75-2.96)1.7 (0.54-4.03)0.83 (0.10-3.03)2.63 (0.84-6.23)
Lung1.05 (0.82-1.33)1.00 (0.78-1.27)1.06 (0.66-1.62)1.02 (0.84-1.22)0.81 (0.59-1.07)0.97 (0.71-1.29)1.51 (1.12-2.00)
Esophagus0.58 (0.12-1.72)1.54 (0.65-3.08)1.16 (0.14-4.24)1.04 (0.47-2.01)1.16 (0.37-2.74)1.16 (0.31-3.01)0.77 (0.09-2.83)
Stomach1.24 (0.56-2.39)0.95 (0.38-1.99)0.00 (0.00-1.97)1.27 (0.72-2.10)1.54 (0.73-2.88)0.61 (0.12-1.81)0.94 (0.19-2.78)
Liver1.89 (0.80-3.78)1.89 (0.8-3.78)0.89 (0.02-5.03)2.06 (1.14-3.46)1.13 (0.30-2.93)1.4 (0.38-3.64)4.20 (1.79-8.41)
Bile duct3.01 (1.09-6.67)2.89 (1.04-6.39)1.93 (0.05-10.9)3.10 (1.52-5.64)3.85 (1.52-8.06)2.17 (0.44-6.43)2.31 (0.28-8.48)
Bladder0.46 (0.09-1.35)1.90 (1.00-3.30)0.58 (0.01-3.27)1.28 (0.71-2.15)0.63 (0.17-1.65)1.36 (0.49-3.01)2.24 (0.81-4.95)
Brain1.36 (0.58-2.72)1.17 (0.46-2.45)1.73 (0.35-5.15)1.17 (0.60-2.09)0.64 (0.13-1.91)1.47 (0.53-3.26)1.93 (0.7-4.26)
Kidney0.89 (0.28-2.11)1.05 (0.38-2.32)1.28 (0.15-4.71)0.92 (0.41-1.77)0.83 (0.22-2.15)1.05 (0.28-2.73)1.12 (0.23-3.32)
Prostate1.29 (0.80-1.97)1.19 (0.73-1.83)2.31 (1.14-4.20)1.08 (0.73-1.53)0.99 (0.57-1.58)1.38 (0.78-2.28)1.67 (0.82-3.04)
Leukemia1.35 (0.73-2.3)0.96 (0.45-1.8)0.00 (0.00-1.35)1.31 (0.82-1.98)1.20 (0.59-2.18)0.99 (0.39-2.06)1.24 (0.45-2.74)
Lymphoma0.96 (0.47-1.74)1.20 (0.64-2.04)0.99 (0.20-2.94)1.10 (0.68-1.69)0.50 (0.16-1.19)1.90 (1.05-3.19)0.92 (0.29-2.17)
Myeloma0.83 (0.22-2.15)1.62 (0.69-3.25)0.77 (0.02-4.36)1.30 (0.64-2.36)0.92 (0.25-2.40)1.22 (0.33-3.16)1.85 (0.5-4.81)