Table 3.

Multivariate analysis to examine the relations of PIK3CA and KRAS mutations with VDR expression in colorectal cancer

Multivariate OR (95% CI)P
Variable independently associated with VDR
    PIK3CA mutation2.36 (1.43-3.91)0.0008
    KRAS mutation1.53 (1.04-2.23)0.029
Other variable
    Mucinous component0.64 (0.43-0.96)0.029

NOTE: Multivariate logistic regression analysis assessing the relations of PIK3CA and KRAS mutations with VDR included age at diagnosis, sex, BMI, tumor location, tumor stage, grade, mucinous component, family history of colorectal cancer, MSI, CIMP, LINE-1, β-catenin, COX-2, p53, p21, and BRAF. Only variables with P < 0.05 are listed.