Table 2.

Multivariable linear regression of DNA methylation (log DPM/μg) by prenatal, early life, adolescent, and adult variables

Linear multivariate model 1
Linear multivariate model 2
Linear multivariate model 2
β (95% CI)β (95% CI)Standardized β
Prenatal
Prenatal smoke exposure−0.34 (−0.65, −0.02)−0.38 (−0.70, −0.07)−0.32
Race
    Black-White0.20 (−0.14, 0.54)0.17 (−0.17, 0.51)0.15
    Hispanic-White−0.14 (−0.45, 0.17)−0.15 (−0.45, 0.16)−0.12
Family socioeconomic status−0.01 (−0.01, 0.001)−0.01 (−0.01, 0.002)−0.18
Early life
    Birth weight (kg)0.33 (−0.06, 0.72)0.28 (−0.11, 0.67)0.26
    Birth length (cm)−0.11 (−0.19, −0.02)−0.11 (−0.19, −0.03)−0.46
Adolescent
    Age at menarche (y)−0.07 (−0.13, −0.004)−0.23
    Childhood passive smoke exposure0.15 (−0.19, 0.48)0.25 (−0.08, 0.58)0.19
Adult
    Current BMI (≥25:<25 kg/m2)−0.19 (−0.46, 0.07)−0.21 (−0.48, 0.05)−0.19
Smoking status
    Former-never−0.02 (−0.30, 0.27)−0.17 (−0.46, 0.12)−0.14
    Current-never0.15 (−0.20, 0.50)0.17 (−0.17, 0.52)0.12
Parity (nulliparous-parous)−0.30 (−0.57, −0.02)−0.25
Age at first birth−0.03 (−0.06, −0.01)−0.35