Table 3.

Median (range) of hormones among breast cancer cases and matched controls

Cases (n = 340)Controls (n = 677)P
2-OH estrone (pg/mL)129 (86-209)125 (82-195)0.20
16α-OH estrone (pg/mL)344 (262-473)349 (254-466)0.80
2-OH:16α-OH estrone ratio0.37 (0.24-0.60)0.37 (0.23-0.59)0.54
Estradiol (pg/mL)8 (4-16)6 (4-12)<0.001
Estrone (pg/mL)26 (15-42)22 (13-37)<0.001
Estrone sulfate (pg/mL)272 (121-669)207 (93-516)<0.001
  • NOTE: Range is median of the bottom quartile (12.5 percentile) to the median of the top quartile (87.5 percentile).