Table 3.

Association of baseline intakes of vitamins B2 and B6 with risk of colorectal adenomas

Baseline dietary vitamin B intake*
P
Q1Q2Q3Q4
Vitamin B2, mg0.39-1.191.20-1.611.62-2.132.14-6.56
All adenomas
    n recurrences/total117/260115/261120/260100/255
    Adjusted RR (95% CI)1.000.94 (0.77-1.15)0.96 (0.79-1.17)0.84 (0.69-1.03)0.14
    Adjusted RR (95% CI)§1.000.94 (0.77-1.16)0.95 (0.77-1.18)0.83 (0.64-1.08)0.23
Advanced lesions
    n recurrences/total28/26030/26131/26019/255
    Adjusted RR (95% CI)1.001.05 (0.64-1.73)1.09 (0.67-1.79)0.70 (0.40-1.22)0.28
    Adjusted RR (95% CI)§1.001.10 (0.66-1.84)1.16 (0.67-2.00)0.78 (0.39-1.57)0.66
    Vitamin B6, mg0.33-1.121.13-1.541.55-2.012.02-6.20
All adenomas
    n recurrences/total108/259122/258112/261110/258
    Adjusted RR (95% CI)1.001.08 (0.88-1.32)0.98 (0.80-1.20)0.95 (0.77-1.16)0.42
    Adjusted RR (95% CI)§1.001.12 (0.90-1.39)1.04 (0.82-1.32)1.05 (0.78-1.41)0.91
Advanced lesions
    n recurrences/total25/25931/25829/26123/258
    Adjusted RR (95% CI)1.001.24 (0.75-2.06)1.08 (0.65-1.80)0.85 (0.49-1.46)0.46
    Adjusted RR (95% CI)§1.001.30 (0.76-2.25)1.18 (0.65-2.15)0.99 (0.46-2.12)0.92
  • * Ranges are based on 2,000 calories/d.

  • Ptrend.

  • Adjusted for age, sex, center, duration of follow-up, aspirin treatment group, and multivitamin use.

  • § Adjusted for age, sex, center, duration of follow-up, aspirin treatment group, multivitamin use, and intake of B2, B6, and folate as appropriate.