Table 3.

The fraction of 6-gingerol glucuronide and sulfate in plasma at Cmax after administration of 1,000, 1,500, and 2,000 mg ginger extract based on enzymatic hydrolysis done in duplicate

Dose (mg)6-gingerol glucuronide (μg/mL)6-gingerol sulfate (μg/mL)Total 6-gingerol
Separate assay (μg/mL)Mixed assay (μg/mL)
1,0000.16 ± 0.150.02 ± 0.030.18 ± 0.120.40 ± 0.20
1,5000.62 ± 0.620.04 ± 0.040.66 ± 0.511.03 ± 0.40
2,0000.62 ± 0.560.33 ± 0.410.95 ± 0.410.91 ± 0.50
  • NOTE: Total 6-gingerols in plasma were assayed after incubating the plasma with the enzymes β-glucuronidase and sulfatase separately (separate assay) and combined (mixed assay).