Table 3.

Age-adjusted ORs for quartiles of other anthropometric characteristics by tumor subtype

Controls
Luminal cases
HER2-overexpressing cases
Triple-negative cases
n (%)n (%)OR* (95% CI)n (%)OR* (95% CI)n (%)OR* (95% CI)
Height, cm
    Quartiles
        <157362 (25)222 (22)1.0 (Reference)11 (28)1.0 (Reference)13 (17)1.0 (Reference)
        157-160362 (25)227 (23)1.0 (0.8-1.3)10 (26)0.9 (0.4-2.1)15 (19)1.1 (0.5-2.3)
        161-165395 (27)301 (30)1.2 (1.0-1.5)11 (28)0.9 (0.4-2.0)26 (34)1.6 (0.8-3.3)
        >165328 (23)258 (26)1.2 (1.0-1.5)7 (18)0.6 (0.2-1.6)23 (30)1.5 (0.7-3.1)
        Trend testP = 0.05P = 0.34P = 0.13
    Continuous (per cm)1.01 (1.00-1.02)1.00 (0.95-1.05)1.02 (0.98-1.05)
Lifetime maximum BMI, kg/m2
    Quartiles
        <25.0362 (25)235 (23)1.0 (Reference)12 (31)1.0 (Reference)15 (19)1.0 (Reference)
        25.0-27.9361 (25)241 (24)1.0 (0.8-1.3)7 (18)0.6 (0.2-1.5)17 (22)1.1 (0.5-2.3)
        28.0-32.3363 (25)261 (26)1.1 (0.9-1.4)7 (18)0.6 (0.2-1.5)21 (27)1.4 (0.7-2.8)
        >32.3361 (25)271 (27)1.1 (0.9-1.4)13 (33)1.0 (0.5-2.3)24 (31)1.5 (0.7-2.8)
        Trend testP = 0.22P = 0.91P = 0.21
    Continuous (per kg/m2)1.01 (1.00-1.02)1.00 (0.95-1.05)1.03 (1.00-1.06)
Lifetime maximum weight, lb
    Quartiles
        ≤140369 (26)224 (22)1.0 (Reference)13 (33)1.0 (Reference)11 (14)1.0 (Reference)
        141-160380 (26)277 (27)1.2 (0.9-1.5)7 (18)0.5 (0.2-1.3)18 (23)1.5 (0.7-3.2)
        161-185349 (24)245 (24)1.1 (0.9-1.4)9 (23)0.7 (0.3-1.7)24 (31)2.2 (1.0-4.5)
        >185349 (24)262 (26)1.2 (0.9-1.5)10 (26)0.7 (0.3-1.7)24 (31)1.9 (0.9-4.0)
        Trend testP = 0.23P = 0.60P = 0.05
    Continuous (per lb)1.00 (1.00-1.01)1.00 (0.99-1.01)1.01 (1.00-1.01)
Weight at age 30 y, lb
    Quartiles
        <120389 (27)263 (26)1.0 (Reference)15 (38)1.0 (Reference)20 (26)1.0 (Reference)
        120-128367 (25)215 (21)0.9 (0.7-1.1)8 (21)0.6 (0.2-1.4)12 (16)0.7 (0.3-1.5)
        129-140323 (22)270 (27)1.2 (1.0-1.5)6 (15)0.5 (0.2-1.2)16 (21)0.9 (0.5-1.8)
        >140368 (25)260 (26)1.1 (0.8-1.3)10 (26)0.7 (0.3-1.6)29 (38)1.5 (0.8-2.7)
        Trend testP = 0.22P = 0.31P = 0.11
    Continuous (per lb)1.00 (0.99-1.01)0.99 (0.96-1.03)1.01 (1.00-1.03)
BMI at age 30 y, kg/m2
    Quartiles
        <20.8362 (25)258 (26)1.0 (Reference)11 (28)1.0 (Reference)21 (27)1.0 (Reference)
        20.8-22.3361 (25)233 (23)0.9 (0.7-1.2)9 (23)0.8 (0.3-2.0)18 (23)0.9 (0.5-1.7)
        22.4-24.3362 (25)279 (28)1.1 (0.9-1.4)6 (15)0.6 (0.2-1.6)11 (14)0.6 (0.3-1.2)
        >24.3362 (25)238 (24)0.9 (0.8-1.2)13 (33)1.2 (0.5-2.8)27 (35)1.4 (0.8-2.5)
        Trend testP = 0.91P = 0.74P = 0.41
    Continuous (per kg/m2)1.00 (0.97-1.02)0.99 (0.90-1.08)1.03 (0.98-1.09)
Weight change (age 30 y vs reference, lb)
Overall
    Weight loss201 (14)71 (7)0.5 (0.3-0.6)3 (8)0.5 (0.1-1.8)9 (12)1.1 (0.5-2.4)
    Weight gain (tertiles)
        <18407 (28)320 (32)1.0 (Reference)13 (33)1.0 (Reference)20 (26)1.0 (Reference)
        18-37416 (29)289 (29)0.9 (0.7-1.1)10 (26)0.7 (0.3-1.7)25 (32)1.1 (0.6-2.0)
        >37423 (29)328 (33)1.0 (0.8-1.2)13 (33)0.9 (0.4-2.0)23 (30)1.0 (0.5-1.8)
    Continuous (per lb)1.00 (1.00-1.01)1.01 (0.99-1.02)1.00 (0.99-1.01)
  • * OR adjusted for age and reference year.

  • P < 0.05.