Table 6.

Association between number of protective haplotypes in CSA and CSB and number of BPDE-induced chromatid breaks per cell

No. protective haplotypesnChromatid breaks per cell, geometric mean (95% CI)*P
01200.26 (0.24-0.29)Reference
11030.22 (0.20-0.24)0.02
2430.21 (0.18-0.25)0.044
3 or 4100.15 (0.11-0.22)0.005
  • * Least-squares means (95% CI) were calculated based on natural log-transformed number of chromatid breaks per cell with adjustment for gender, current smoking status, and seeding count; then, they were converted to their exponential form [geometric mean (95% CI)].