Table 2.

Association between major principal components of CSA and CSB and number of BPDE-induced chromatid breaks per cell

GenePrincipal componentEffect per each unit of change of principal component
P*Variance explained (%)Cumulative variance explained (%)P of Likelihood ratio test
Estimate95% CI
CSAPC10.920.85-0.980.02147.590.10.02
PC20.940.87-1.010.07425.9
PC31.040.97-1.120.30016.7
CSBPC11.040.96-1.120.35130.089.70.018
PC21.081.01-1.170.04622.9
PC30.940.87-1.010.10522.1
PC40.920.85-0.990.04214.7
  • * Adjustment for gender, seeding count, and current smoking status was included in the multiple linear regression model.

  • Estimate is ratio of mean number of breaks per cell for each unit of change of principal component.