Table 4.

Genotype distribution and association analysis of six single-nucleotide polymorphisms at the 1p12-13 region

Single-nucleotide polymorphismGenotypeControls [n (%)]Patients [n (%)]Odds ratio* (95% CI)P
rs4659200CC54 (39.7)85 (42.5)1.0 (reference)0.18
TC57 (41.9)89 (44.5)0.9 (0.62-1.60)
TT25 (18.4)26 (13.0)0.7 (0.35-1.26)
rs3765945TT5574 (37.2)1.0 (reference)0.56
CT71 (52.2)109 (54.8)1.1 (0.72-1.81)
CC10 (7.4)16 (8.0)1.2 (0.50-2.82)
rs2145418TT87 (64.0)44 (22.3)1.0 (reference)<0.0001
TG34 (25.0)85 (43.1)5.0 (2.80-8.83)
GG15 (11.0)68 (34.5)9.2 (4.50-18.6)
rs7515409TT54 (26.7)65 (29.3)1.0 (reference)0.27
CT112 (55.4)113 (50.9)0.8 (0.54-1.31)
CC33 (16.3)44 (19.8)1.1 (0.62-1.97)
rs4658973TT60 (30.9)127 (59.3)1.0 (reference)<0.0001
GT95 (48.9)81 (37.9)0.4 (0.26-0.62)
GG39 (20.1)6 (2.8)0.07 (0.03-0.2)
rs1241TT52 (38.5)92 (45.8)1.0 (reference)0.08
CT75 (55.6)92 (45.8)0.7 (0.44-1.09)
CC8 (5.9)17 (8.4)1.2 (0.49-1.16)
  • * Crude odds ratio.

  • P value corresponding to a codominant model.