Table 3.

Energy-adjusted medians and IQRs of daily intakes of total flavonoids, flavonoid subgroups, and flavonoid-rich foods among participants during the PPT by adenoma recurrence

Dietary component*Overall
No recurrence
Advanced recurrence
Any recurrence
Median (IQR)Median (IQR)Median (IQR)PMedian (IQR)P
1,8591,123123123/1123736736/1,123
Flavonoids (in mg/1,000 kcal)
    Total flavonoids76.2 (50.9-106.1)76.1 (50.1-105.3)72.2 (51.1-104.6)0.7476.3 (52.2-106.4)0.53
        Anthocyanins10.1 (5.70-15.6)10.2 (5.61-16.0)9.85 (5.68-13.91)0.529.83 (5.82-15.3)0.30
        Flavan-3-ols17.3 (10.2-38.6)17.8 (10.4-39.4)15.7 (9.20-29.9)0.1316.7 (9.92-37.6)0.36
        Flavanones22.7 (10.6-36.9)21.6 (9.88-35.3)24.5 (14.4-44.8)0.00524.2 (12.5-39.5)0.002
        Flavones0.73 (0.46-1.10)0.73 (0.46-1.09)0.72 (0.43-1.11)0.560.73 (0.45-1.11)0.59
        Flavonols12.0 (9.12-17.3)12.3 (8.19-17.6)10.3 (7.55-14.1)0.00211.5 (8.04-17.1)0.30
        Isoflavonoids0.08 (0.04-0.13)0.08 (0.04-0.14)0.07 (0.04-0.10)0.0070.07 (0.05-0.13)0.46
Flavonoid-rich foods (in g/1,000 kcal)
    Bananas23.5 (10.5-43.1)23.5 (10.7-42.6)23.6 (12.0-45.2)0.5723.4 (10.2-43.6)0.91
    Grapefruits4.36 (0-15.9)3.84 (0-14.6)6.22 (1.23-18.3)0.025.20 (0.77-18.0)0.004
    Oranges10.5 (3.55-23.96)10.2 (3.41-22.8)11.9 (4.19-28.6)0.5111.3 (4.10-25.9)0.21
    Citrus fruit juices34.1 (8.04-78.1)32.9 (7.32-76.8)40.9 (9.98-84.6)0.1036.7 (8.78-81.9)0.04
    Other fruits§12.3 (3.72-28.3)12.7 (3.74-30.0)9.70 (3.60-25.2)0.2511.1 (3.66-26.9)0.25
    Other fruit juices9.31 (1.30-32.4)9.92 (1.41-33.0)10.1 (1.05-30.7)0.808.25 (1.17-29.4)0.12
    Dry beans8.58 (3.63-19.4)8.85 (3.67-20.0)6.17 (3.41-13.43)0.0068.02 (3.52-19.0)0.30
    Peas4.86 (2.44-8.76)4.88 (2.37-8.74)4.75 (2.19-7.91)0.464.81 (2.47-8.82)0.80
    Other vegetables25.4 (12.3-45.7)25.9 (11.8-46.6)20.8 (9.76-35.6)0.00925.0 (13.2-44.4)0.99
    Tea7.05 (0-49.8)7.60 (0-52.5)3.00 (0-38.4)0.076.30 (0-47.6)0.48
  • NOTE: Daily intakes of flavonoids and flavonoid-rich foods (contributed ≥5% of total flavonoid or ≥10% of flavonoid subgroup consumption) are for the first 3 y of the PPT and were energy adjusted by dividing through total caloric intake in 1,000 kcal (4.184 MJ). Adenomatous polyp recurrence (any or advanced) was diagnosed through postintervention at year 4.

  • * Energy-adjusted intakes of flavonoids and flavonoid-rich foods are presented as energy-adjusted medians and interquartile ranges with P values for differences in energy-adjusted means determined by Wilcoxon rank sum test.

  • Comparison between the adenoma recurrence group to the no adenoma recurrence group.

  • Comparison between the advanced adenoma recurrence group to the no adenoma recurrence group.

  • § Other fruits (46% grapes, 31% plums, and 23% pineapples).

  • Other fruit juices (50% apple juice, 25% cranberry juice, and 25% grape juice).

  • Other vegetables (30% white onions, 5% red onion, 27% cucumbers, 16% celery, 12% radishes, and 10% pepper).