Table 3.

Association of alcohol consumption at baseline and average lifetime alcohol consumption with prostate cancer

Intake (g/d)Alcohol consumption at baseline
Average lifetime alcohol consumption
Cases (n)Relative risk*Relative risk (95% CI)†Cases (n)Relative risk*Relative risk (95% CI)
All cases
02040.950.95 (0.81-1.12)200.820.82 (0.51-1.29)
0.1-4.96151.001.002601.001.00
5-14.97451.000.99 (0.89-1.11)4821.021.03 (0.88-1.21)
15-29.95310.960.95 (0.84-1.08)4211.051.08 (0.91-1.27)
30-59.94221.021.03 (0.90-1.18)2830.981.02 (0.85-1.23)
≥601380.860.88 (0.72-1.08)1421.031.09 (0.86-1.39)
Prostate cancer stage (localized cases)
0770.870.87 (0.67-1.13)100.920.91 (0.46-1.70)
0.1-4.92541.001.00931.001.00
5-14.92960.980.97 (0.86-1.16)2351.151.16 (0.91-1.48)
15-29.92270.990.98 (0.81-1.19)2151.221.24 (0.96-1.61)
30-59.91901.011.02 (0.83-1.25)1320.971.01 (0.76-1.35)
≥60650.730.76 (0.57-1.02)851.041.11 (0.79-1.57)
Prostate cancer stage (advanced cases)
0330.740.74 (0.50-1.10)40.800.81 (0.29-2.25)
0.1-4.91361.001.00651.001.00
5-14.91610.970.97 (0.77-1.23)1100.910.90 (0.65-1.25)
15-29.9930.730.73 (0.55-0.97)760.730.72 (0.50-1.03)
30-59.9760.770.77 (0.57-1.05)660.980.96 (0.65-1.40)
≥60380.990.98 (0.66-1.44)331.341.28 (0.79-2.07)
Prostate cancer grade (low-grade cases)§
0930.990.99 (0.76-1.29)771.181.16 (0.59-2.25)
0.1-4.93421.001.002431.001.00
5-14.93790.950.95 (0.79-1.14)2630.981.01 (0.77-1.33)
15-29.92540.790.79 (0.64-0.98)1671.041.11 (0.84-1.47)
30-59.92130.870.91 (0.73-1.13)1490.810.89 (0.65-1.22)
≥60670.600.65 (0.46-0.91)440.971.13 (0.78-1.62)
Prostate cancer grade (high-grade cases)
0440.900.91 (0.64-1.28)40.560.56 (0.20-1.53)
0.1-4.91541.001.00891.001.00
5-14.91750.970.97 (0.78-1.22)1320.840.84 (0.63-1.11)
15-29.91200.950.95 (0.73-1.23)1040.830.83 (0.61-1.13)
30-59.91051.071.07 (0.82-1.40)831.021.03 (0.74-1.44)
≥60461.181.17 (0.81-1.67)431.231.22 (0.79-1.89)
  • * Stratified by age (1-year categories) and study center.

  • Stratified by age (1-year categories) and study center; adjusted for weight (continuous), height (continuous), total physical activity (5 categories), smoking status (4 categories), and energy intake without energy from alcohol (continuous).

  • Tumors were classified as localized (T0, T1, or T2; N0 or Nx; and M0; or stage-coded in the recruitment center as localized) or advanced (T3 or T4, N1+, and/or M1, or stage-coded in the recruitment center as metastatic).

  • § Tumors were divided into low grade (Gleason score, 2-6 or equivalent; cases coded as well or moderately differentiated) or high grade (Gleason score, ≥7 or equivalent; cases coded as poorly differentiated or undifferentiated).