Table 5.

Effect of teeth loss on cancer risk stratified by smoking status

SiteSmoking statusnNo. remaining teeth
PtrendPeffect modification
21
9-20
0-8
OR (95% CI)nOR (95% CI)nOR (95% CI)n
Head and neckNever1241.00 (reference)621.30 (0.65-2.62)314.24 (1.56-11.49)310.008
Former1451.00 (reference)641.55 (0.71-3.40)491.13 (0.42-3.07)320.675
Current1591.00 (reference)700.56 (0.23-1.35)422.08 (0.62-7.01)470.6490.700
Pack-years = 01241.00 (reference)621.30 (0.65-2.62)314.24 (1.56-11.49)310.008
0 < Pack-years ≤ 401541.00 (reference)751.44 (0.70-2.96)460.80 (0.22-2.94)330.700
Pack-years > 401431.00 (reference)550.74 (0.34-1.63)450.66 (0.37-1.62)430.3520.030
EsophagusNever411.00 (reference)142.69 (0.30-23.79)99.50 (1.33-67.98)180.021
Former1401.00 (reference)620.77 (0.38-1.54)381.57 (0.63-3.89)400.569
Current1721.00 (reference)631.71 (0.59-4.95)591.03 (0.36-2.89)500.9160.922
Pack-years = 0411.00 (reference)142.69 (0.30-23.79)99.50 (1.33-67.98)180.021
0 < Pack-years ≤ 401091.00 (reference)550.48 (0.14-1.63)260.96 (0.23-3.92)280.636
Pack-years > 401981.00 (reference)680.85 (0.44-1.65)701.10 (0.71-1.71)600.7910.569
LungNever2531.00 (reference)1451.01 (0.68-1.50)691.10 (0.65-1.88)390.744
Former3641.00 (reference)1431.07 (0.68-1.66)1141.10 (0.66-1.83)1070.697
Current2911.00 (reference)1061.87 (0.99-3.54)963.23 (1.39-7.50)890.0050.286
Pack-years = 02531.00 (reference)1451.01 (0.68-1.50)691.10 (0.65-1.88)390.744
0 < Pack-years ≤ 401961.00 (reference)890.66 (0.31-1.44)520.73 (0.31-1.68)550.398
Pack-years > 404551.00 (reference)1581.09 (0.57-2.09)1561.96 (0.90-4.27)1410.1190.118
  • NOTE: OR adjusted for age, drinking status (never, former, current), vegetable and fruit intake, BMI, and regular exercise.