Table 4.

Association between MTHFR C667T and A1298C diplotypes and risk of meningioma

MTHFR diplotype 677_1298Cases (%)Controls (%)OR (95% CI)PORPdiplotype
CC_AA62 (9.8)108 (17.0)Reference0.0019
CC_AC144 (22.9)124 (19.5)2.03 (1.37-3.01)0.0004
CC_CC56 (8.9)74 (11.6)1.33 (0.83-2.12)0.24
CT_AA150 (23.8)137 (21.5)1.93 (1.30-2.85)0.0010
CT_AC153 (24.3)128 (20.1)2.11 (1.42-3.12)0.0002
TT_AA65 (10.3)65 (10.2)1.76 (1.10-2.81)0.018
TT_AC01 (0.16)
CT_CC00
TT_CC00
CC_AA62 (9.8)108 (17.0)Reference0.0015
CT/TT_AA215 (34.1)202 (31.7)1.88 (1.30-2.72)0.0008
CC_AC/CC200 (31.7)198 (31.1)1.77 (1.22-2.56)0.0025
CT/TT_AC/CC153 (24.3)129 (20.3)2.09 (1.41-3.10)0.0002