Table 4.

Results from the Mantel statistics using haplotype sharing

P values for single SNPs
Global P
All cases and controls0.2220.2220.2220.1460.1760.2220.146
Never and weak smoker (<20 pack-years)0.8880.8680.8880.9390.9040.9210.868
Strong smoker (≥20 pack-years)0.022*0.022*0.011*0.0070.010*0.011*0.007
  • NOTE: P values were derived by 10,000 Monte Carlo permutations. Global P value is derived by a step-down min-P algorithm to adjust for multiple testing.

  • * P < 0.05.

  • P < 0.01.