Table 3.

Association between TCF7L2 rs7903146 polymorphism and colon cancer by recent use of aspirin/NSAIDS

Recent aspirin/NSAID use
No recent aspirin/NSAID use
P interaction
Controls
Cases
Controls
Cases
nnOR* (95% CI)nnOR (95% CI)
TCF7L2
    CC3942691.005584521.19 (0.98-1.46)0.0001
    CT3391860.80 (0.63-1.02)3974491.65 (1.35-2.03)
    TT75350.68 (0.44-1.05)70811.64 (1.14-2.34)
    P trend0.030.001
TCF7L2
    CC3942691.005584521.19 (0.98-1.46)
    CT and TT4142210.78 (0.62-0.98)4675301.65 (1.35-2.02)
  • * OR and 95% CI adjusted for age, center, race, sex, BMI, and physical activity.