Table 2.

VDR expression characteristics of the biopsies, stratified by the histology

Normal, n (%)
Metaplasia, n (%)
Dysplasia, n (%)
Bronchoscopy-detected cancers, n (%)
Squamous cell carcinoma TMA, n (%)
Adenocarcinoma TMA, n (%)
NuclearCytoplasmicNuclearCytoplasmicNuclearCytoplasmicNuclearCytoplasmicNuclearCytoplasmicNuclearCytoplasmic
Intensity
    017 (19)15 (17)15 (23)13 (20)3 (17)10 (23)3 (17)5 (28)28 (64)10 (59)
    118 (21)25 (29)10 (16)16 (24)6 (33)14 (32)7 (39)9 (50)8 (18)3 (18)
    250 (57)46 (53)33 (52)37 (56)9 (50)20 (46)3 (75)3 (75)8 (44)4 (22)8 (18)4 (24)
    33 (3)1 (1)6 (9)1 (25)1 (25)
Percentage of cells (%)
    017 (19)15 (17)15 (23)13 (20)4 (21)10 (23)3 (17)5 (28)28 (64)12 (63)
    <103 (3)7 (8)4 (6)2 (3)1 (2)
    10-5016 (18)12 (14)12 (19)14 (22)1 (5)4 (9)1 (25)5 (28)3 (17)5 (11)1 (5)
    >5051 (59)53 (61)33 (52)36 (55)14 (74)30 (68)4 (100)3 (75)10 (56)10 (56)10 (23)6 (32)
Distribution
    No staining17 (21)15 (18)15 (25)13 (21)3 (21)3 (18)5 (28)10 (59)
    Basal2 (2)5 (6)2 (3)1 (2)1 (6)0
    Suprabasal19 (23)17 (20)8 (14)17 (28)2 (14)1 (6)1(6)3 (18)
    Full44 (54)46 (55)34 (58)30 (49)9 (64)2 (100)2 (100)12 (71)12 (67)4 (24)
Cytoplasmic vs nuclear intensity
    Nuclear > cytoplasmic25 (29)22 (34)7 (39)9 (53)30 (68)
    Equal38 (44)26 (41)8 (44)4 (100)4 (24)5 (11)
    Cytoplasmic > nuclear24 (29)16 (25)3 (17)4 (24)9 (21)
  • Abbreviation: TMA, tumor microarray.