Table 2.

Summary random effects estimates by screening procedure

Proceduren*PPV (95% CI)Se (95% CI)Sp (95% CI)
Mammogram19Fixed79 (77-80)93 (92-94)62 (60-64)
Random79 (74-84)95 (93-97)61 (54-68)
Filled§92 (88-95)
CBE7Fixed78 (76-80)93 (92-95)29 (25-33)
Random82 (73-88)94 (91-96)26 (18-36)
Filled76 (65-84)92 (88-95)
Pap smear26Fixed70 (69-72)91 (90-92)47 (45-49)
Random76 (69-81)93 (91-95)48 (40-57)
Filled68 (61-74)88 (83-91)
PSA test6Fixed76 (73-79)71 (68-74)73 (70-76)
Random79 (71-85)71 (68-74)73 (62-81)
Filled
DRE10Fixed63 (61-65)74 (71-76)60 (58-62)
Random59 (52-66)75 (66-82)60 (55-66)
Filled67 (59-74)
FOBT13Fixed62 (60-64)78 (76-80)77 (76-79)
Random62 (50-73)82 (73-88)78 (71-83)
Filled
Screening endoscopy13Fixed56 (54-59)82 (80-84)85 (84-86)
Random51 (41-62)79 (73-84)90 (85-93)
Filled83 (77-88)83 (77-88)
  • Abbreviations: PPV, positive predictive value; Se, sensitivity; Sp, specificity; CI, confidence interval.

  • * Number of study subgroups.

  • Fixed effects summary estimate.

  • Random effects summary estimate.

  • § Summary random effects estimate adjusted for publication bias.