Table 1.

Kentucky Colon Cancer Study participant characteristics

Controls (n = 721)Cases (n = 561)
Mean age (SD)59.0 (10.9)64.1 (10.8)
Sex (%)
    Female442 (61.3)287 (51.2)
    Male279 (38.7)274 (48.8)
Race (%)
    African American23 (3.2)25 (4.5)
    Caucasian679 (94.2)527 (94.1)
    Other19 (2.6)8 (1.4)
Regular NSAID use (%)*
    Regular445 (67.4)309 (62.3)
    Never215 (29.8)188 (33.5)
    Missing61 (8.5)64 (11.4)
Mean body mass index (kg/m2; SD)28.1 (6.2)29.3 (6.1)
Family history of colorectal cancer (%)
    Yes166 (23.0)177 (31.6)
    No496 (68.8)330 (58.8)
    Missing59 (8.2)54 (9.6)
rs6983267 (%)
    TT175 (24.3)103 (18.4)
    GT348 (48.3)272 (48.5)
    GG198 (27.5)186 (33.2)
  • * Regular NSAID use was defined as reporting ever use of aspirin or NSAID at least twice a week for at least 1 mo.

  • Lifestyle variables were obtained from the RFQ. Body mass index was calculated based on self-reported current weight and height (kg/m2). Seventy cases and sixty-nine controls were missing on weight or height.

  • A positive family history of colorectal cancer was defined as self-report of colorectal cancer in ≥1 first-degree relative.