Table 4.

Gene panels constructed from classifier for hypermethylation detection in saliva

Gene panelSensitivity (test positive/disease positive)Specificity (test negative/total samples)
AGTR_P41_F
ESR1_E298_R
FLT1_E444_F
NOTCH3_E403_F69% (9/13)83% (19/23)
GABRB3_E42_F
IL11_P11_R
INSR_P1063_R
NOTCH3_E403_F
NTRK3_E131_F
PXN_P308_F77% (10/13)87% (20/23)
ERBB4_P255_F
IL11_P11_R
PTCH2_P37_F
TMEFF1_P234_F
TNFSF10_E53_F
TWIST1_P44_R62% (8/13)100% (23/23)
ADCYAP1_P455_R
CEBPA_P706_F
EPHA5_E158_R
FGF3_E198_R
HLF_E192_F
IL11_P11_R
INSR_P1063_R
NOTCH3_E403_F69% (9/13)96% (22/23)
AGTR1_P41_F
BMP3_P56_R
FGF8_P473_F
NTRK3_E131_F62% (8/13)87% (20/23)
ERBB4_P255_F
FLT_P615_R
INSR_P1063_R
IRAK3_P13_F
KDR_P445_R
NTRK_P636_R
PTCH2_P37_F
PXN_P308_F
RASGRF1_E16_F
WT1_P853_F69% (9/13)78% (18/23)
ESR1_E298_R
ETV1_P235_F
GAS7_E148_F
IL11_P11_R
PKD2_P287_R
TMEFF1_P234_F
WNT2_E109_R62% (8/13)83% (19/23)
EPHA5_E158_R
FGF3_P171_R
GALR1_E52_F
IL11_P11_R
INSR_P1063_R
KDR_E79_F
p16_seq_47_S188_R62% (8/13)83% (19/23)
AGTR1_P41_F
ERBB4_P255_F
EYA4_P508_F
FLT1_P302_F
IHH_E186_F
NTRK3_E131_F
NTRK3_P752_F
TFPI2_P9_F62% (8/13)78% (18/23)