Table 3.

Genes comprising the classifier and their function

Methylated genesLoci and strand of methylationFunction
ADCYAP1P398_FCell signaling
P455_R
AGTR1P41_FCell signaling
BMP3P56_RCell signaling, cell differentiation
CEBPAP706_FRegulation of transcription, cell differentiation
EPHA5E158_RCell signaling
ERBB4P255_FCell signaling, cell proliferation, development
ESR1E298_RRegulation of transcription, cell signaling, cell growth
ETV1P235_FRegulation of transcription
EYA4P508_FRegulation of transcription
FGF3E198_RCell cycle control, cell signaling, cell proliferation, development
P171_R
FGF8P473_FCell cycle control, cell signaling, cell proliferation, development
FLT1E444_FAngiogenesis, cell proliferation, cell differentiation
P302_F
P615_R
GABRB3E42_FCell signaling
GALR1E52_FCell signaling
GAS7E148_FCell cycle control, cell differentiation, development
HLFE192_FRegulation of transcription, development
IHHE186_FCell signaling, development
IL11P11_RCell signaling, cell differentiation
INSRP1063_RDevelopment
IRAK3P13_FCell signaling
KDRE79_FAngiogenesis, cell signaling, cell differentiation
P445_R
NOTCH3E403_FRegulation of transcription, cell signaling, cell differentiation
NTRK3E131_FCell signaling, cell differentiation, development
P636_R
P752_F
p16seq_47_S188_RCell cycle control
PKD2P287_RCell adhesion, development
PTCH2P37_FCell differentiation, development
PXNP308_FCell adhesion, cell signaling, development
RASGRF1E16_FCell adhesion, development
TFPI2P9_FBlood coagulation
TMEFF1P234_FCell signaling
TNFSF10E53_FApoptosis
TWIST1P44_RRegulation of transcription, cell differentiation, development
WNT2E109_RCell signaling, development
WT1P853_FRegulation of transcription, cell cycle control