Table 2.

Adjusted PMD and 95% CI according to levels of dietary soy isoflavones

Soy isoflavones (mg/d)n (total = 3,315)Mean (95% CI) PMD (%)
Method 1*Method 2
All subjects
    Q1 (<7.7)82921.0 (19.9-22.2)26.3 (24.8-27.8)
    Q2 (>7.7-14.1)82922.4 (21.3-23.6)27.7 (26.2-29.2)
    Q3 (>14.1 to ≤23.5)82921.5 (20.3-22.6)26.7 (25.2-28.2)
    Q4 (>23.5)82820.4 (19.2-21.6)25.7 (21.1-27.2)
    Ptrend0.2800.280
    Q1 + Q2 + Q32,48721.7 (21.0-22.3)26.9 (25.8-28.1)
    Q482820.4 (19.2-21.6)25.7 (21.1-27.2)
    Ptrend0.0550.055
Premenopausal
    Q1 (<7.7)7032.2 (27.7-36.7)35.1 (30.2-40.4)
    Q2 (>7.7-14.1)8732.0 (28.1-35.9)34.9 (30.3-39.5)
    Q3 (>14.1 to ≤23.5)7733.4 (29.3-37.5)36.3 (31.3-41.3)
    Q4 (>23.5)8633.8 (29.6-38.0)36.7 (31.9-41.5)
    Ptrend0.5650.565
    Q1 + Q2 + Q323432.5 (30.1-34.9)35.4 (32.0-38.8)
    Q48633.7 (29.6-37.9)36.6 (31.9-41.3)
    Ptrend0.5830.583
Postmenopausal
    Q1 (<7.7)75919.8 (18.6-21.0)23.3 (21.8-24.9)
    Q2 (>7.7-14.1)74221.4 (20.3-22.6)24.9 (23.5-26.4)
    Q3 (>14.1 to ≤23.5)75220.2 (19.0-21.4)23.7 (22.2-25.2)
    Q4 (>23.5)74219.0 (17.7-20.2)22.4 (21.0-24.0)
    Ptrend0.2180.218
    Q1 + Q2 + Q32,25320.5 (19.8-21.2)24.0 (22.9-25.2)
    Q474218.9 (17.7-20.2)22.5 (21.0-24.0)
    Ptrend0.0350.035
  • NOTE: Adjusted for age at mammography, BMI at mammography (kg/m2), education (no formal education, primary school, secondary school, A level/university), menopausal status (for all subjects), parity (0,1-2, 3-4, ≥5), and total calories (kcal).

  • * The LSM was calculated using an analysis of covariance with weighted average method.

  • The LSM was calculated using an analysis of covariance by assigning equal weights to the strata included in the analysis. This method was used in our previous study (15).