Table 2.

Frequency distribution of demographic variables and putative risk factors of lung cancer in ILCCO pooled data set for DNA repair pooled analysis

Cases, n (%)Controls, n (%)
Total8,4549,344
Study ID name (genotyping method)
    Norway (TaqMan and APEX; ref. 14)334 (3.95)413 (4.4)
    GenAir (TaqMan and PE/DHPLC; ref. 10)116 (1.4)1,077 (11.5)
    Kyushu (RFLP; ref. 34)190 (2.3)108 (1.2)
    University of California at Los Angeles (RFLP; ref. 29)497 (5.9)902 (9.7)
    Lung Cancer of Young (MassArray-PE; ref. 32)270 (3.2)222 (2.4)
    NCI-Maryland (TaqMan; ref. 30)490 (5.8)678 (7.3)
    INSERM-CEPH (BeadArray; ref. 11)151 (1.8)172 (1.8)
    M. D. Anderson (TaqMan; ref. 24)342 (4.0)362 (3.9)
    Harvard (TaqMan; ref. 31)2,253 (26.6)1,418 (15.2)
    German Cancer Research Center (LightCycler and RFLP; ref. 33)1,020 (12.1)425 (4.6)
    IARC (TaqMan and Amplifluor; ref. 12)2,210 (26.1)2,845 (30.5)
    NCI-China 2 (TaqMan; ref. 35)119 (1.4)114 (1.2)
    Singapore 1 (TaqMan; ref. 36)125 (1.5)162 (1.7)
    Hawaii-P (RFLP; ref. 13)337 (4.0)446 (4.8)
Sex
    Male5,332 (63.1)5,698 (61.0)
    Female3,122 (36.9)3,646 (39.0)
Age (y)
    <40163 (1.9)431 (4.6)
    40-491,152 (13.6)1,539 (16.5)
    50-592,362 (27.9)2,838 (30.4)
    60-692,693 (31.8)2,854 (30.5)
    70-791,835 (21.7)1,568 (16.8)
    ≥80249 (2.9)114 (1.2)
Smoking status
    Never878 (10.4)3,326 (35.6)
    Ever7,547 (89.3)5,999 (64.2)
    Former2,688 (31.8)3,211 (34.4)
    Current4,788 (56.6)2,721 (29.1)
Education
    Low1,249 (18.7)1,715 (21.0)
    Medium3,421 (51.2)3,761 (46.0)
    High2,006 (30.0)2,698 (33.0)
Ethnicity
    Non-Hispanic Whites7,404 (87.6)8,033 (86.0)
    Asians600 (7.1)605 (6.5)
    Native Hawaiian/other Pacific Islander85 (1.0)102 (1.1)
    Black or African American251 (3.0)359 (3.8)
    Hispanic or Latino96 (1.1)213 (2.3)
    American Indian or Alaska Native5 (0.1)3 (0.03)
    Other8 (0.1)27 (0.3)
Histology
    Squamous cell carcinoma2,399 (28.4)
    Small cell carcinoma1,052 (12.4)
    Large cell carcinoma498 (5.9)
    Adenocarcinoma2,923 (34.6)
    Others, not otherwise specified1,416 (12.9)
  • NOTE: Education level: low, no education to junior high school; medium, high school or technical school level; high, university level and above. PE, primer extension; APEX, arrayed primer extension.