Table 3.

ICCs for the reliability of the three tissue core samples

AntigenAll tumors*
Invasive
Borderline
≤10 y
>10 y
ICCρ§ICCρICCρICCρICCρ
Ki-670.940.930.930.920.961.000.890.880.950.94
PR0.950.930.950.930.920.930.950.930.950.93
p530.970.960.970.960.800.750.980.970.960.95
ER-α0.910.910.920.920.790.760.890.920.910.90
WT-10.980.980.990.990.850.93>0.990.990.960.96
CK70.940.960.940.950.920.960.950.960.930.95
CK200.970.870.970.87n/an/an/an/a0.970.87
  • Abbreviation: n/a, not applicable.

  • * Range for the number of observations used (with nonmissing data): all tumors 413 to 486; invasive 376 to 400; borderline 45 to 52; ages ≤10 y, 154 to 181; ages >10 y, 178 to 303.

  • Age was dichotomized into ages ≤10 and >10 y at of the time of staining.

  • ICC were calculated using the using the log transformed values for each stain.

  • § ρ is the mean Spearman correlation of three cores from each tumor sample.

  • Too many missing observations (n = 47) to perform the calculation.