Relationship between a history of migraine and risks of invasive ductal and invasive lobular breast carcinomas
| Controls (n = 1,474) | Ductal carcinoma (n = 1,199) | Lobular carcinoma (n = 739) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n (%) | n (%) | OR* (95% CI) | n (%) | OR* (95% CI) | ||||||
| Never diagnosed with migraine | 1,202 (82) | 1,037 (87) | 1.00 (reference) | 630 (85) | 1.00 (reference) | |||||
| Ever diagnosed with migraine | 272 (19) | 162 (14) | 0.67 (0.54-0.82)† | 109 (15) | 0.68 (0.52-0.90)† | |||||
| Age at migraine diagnosis (y) | ||||||||||
| <20 | 73 (5) | 32 (3) | 0.50 (0.33-0.76)† | 23 (3) | 0.55 (0.33-0.91)† | |||||
| 20-39 | 110 (8) | 80 (7) | 0.83 (0.62-1.13) | 48 (7) | 0.77 (0.53-1.12) | |||||
| ≥40 | 89 (6) | 50 (4) | 0.62 (0.43-0.89)† | 36 (5) | 0.62 (0.41-0.95)† | |||||
| P value for difference across age categories | 0.52 | 0.85 | ||||||||
| Ever use of prescription migraine medications | ||||||||||
| No | 127 (9) | 67 (6) | 0.58 (0.43-0.79)† | 53 (7) | 0.65 (0.46-0.93)† | |||||
| Yes | 144 (10) | 92 (8) | 0.73 (0.56-0.97)† | 55 (8) | 0.69 (0.49-0.97)† | |||||
| P value for difference across medication categories | 0.25 | 0.98 | ||||||||