Table 2.

HR and 95% CI of lung cancer according to physical activity levels and inflammatory markers

No. casesPerson-years*HR (95% CI)PtrendHR (95% CI)Ptrend
Episodes of sweat-inducing activities/wk
    010536,75311
    1-31010,8620.44 (0.23-0.85)0.45 (0.23-0.87)
    ≥4199,6110.75 (0.45-1.24)0.080.76 (0.46-1.26)0.09
City blocks walked/d
    07325,11711
    1-114419,6330.93 (0.63-1.37)0.92 (0.62-1.35)
    ≥121712,2920.53 (0.31-0.90)0.030.52 (0.30-0.89)0.02
Flights of stairs climbed/d
    0-14417,71511
    2-56020,2241.53 (1.02-2.29)1.53 (1.02-2.29)
    >53019,2540.84 (0.52-1.36)0.580.86 (0.53-1.40)0.67
Total physical activity index (kcal/wk)§
    0-1746518,53111
    175-8743819,1200.72 (0.47-1.09)0.72 (0.48-1.09)
    ≥8753119,3580.55 (0.35-0.86)0.010.56 (0.35-0.87)0.01
Heart rate (30 s)
    21-332712,06511
    34-427033,9250.93 (0.59-1.46)0.95 (0.60-1.49)
    >423711,2351.30 (0.80-2.16)0.271.25 (0.75-2.09)0.35
WBC tertile (×103/μL)
    <6.41619,6051
    6.4-7.95019,4212.74 (1.53-4.90)
    ≥86818,0192.81 (1.58-5.01)0.001
Albumin tertile (g/dL)
    <4.65219,3071
    4.6-4.85120,3211.02 (0.69-1.52)
    ≥4.93117,4270.85 (0.54-1.34)0.52
  • * Total person-years for cases and noncases in category of activity.

  • Models are adjusted for age, sex, pack-years of smoking, time since smoking cessation, body mass index, alcohol intake, and education.

  • Models are adjusted for all variables in †, plus WBC count.

  • § Kilocalories per week from city blocks walked, flights of stairs climbed, and sweat-inducing activities (see Materials and Methods).