Table 3.

TSG methylation in 34 primary tumors and corresponding ipsilateral duct lavage samples

GeneMethylation prevalence
Median methylation fraction
Correlation*
Tumor FNA (%)NDL (%)PTumor FNANDLPCoefficientP
Cyclin D237.18.70.0040.1980.0780.4280.040.846
APC38.213.00.0190.3790.0410.005-0.140.431
HIN144.113.30.0050.7300.1140.0040.070.687
RASSF1A61.88.7<0.00010.4310.0640.045-0.210.238
RAR-β226.56.50.0310.0280.3100.166-0.060.744
  • * Spearman correlation between paired methylation fractions.