Age-adjusted ORs for variants of selected apoptosis/cell cycle–related SNPs in the NCI adult brain tumor study, Non-Hispanic Whites only, by gender
| Genotype | Males | Females | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n | OR (95% CI) | n | OR (95% CI) | |||||||
| Glioma | ||||||||||
| CCND1 (rs603965) | GG | 54 | 1.0 (reference) | 39 | 1.0 (reference) | |||||
| AG | 98 | 1.3 (0.8-2.0) | 81 | 1.4 (0.8-2.2) | ||||||
| AA | 37 | 1.6 (0.9-2.9) | 32 | 1.0 (0.6-1.9) | ||||||
| CCNH (rs2266690) | TT | 125 | 1.0 (reference) | 86 | 1.0 (reference) | |||||
| CT | 53 | 0.8 (0.5-1.3) | 59 | 1.6 (1.0-2.4) | ||||||
| CC | 12 | 2.0 (0.7-5.3) | 9 | 2.5 (0.9-7.2) | ||||||
| MDM2 (rs769412) | AA | 174 | 1.0 (reference) | 139 | 1.0 (reference) | |||||
| AG | 14 | 0.5 (0.2-0.9) | 16 | 0.8 (0.4-1.6) | ||||||
| GG | 1 | — | 0 | — | ||||||
| Meningioma | ||||||||||
| CASP8 (rs13113) | TT | 10 | 1.0 (reference) | 35 | 1.0 (reference) | |||||
| AT | 14 | 0.9 (0.4-2.1) | 52 | 0.8 (0.4-1.3) | ||||||
| AA | 4 | 0.6 (0.2-2.1) | 13 | 0.5 (0.2-1.1) | ||||||
| CASP8 (rs1045485) | GG | 22 | 1.0 (reference) | 69 | 1.0 (reference) | |||||
| GC | 4 | 0.5 (0.2-1.6) | 31 | 1.9 (1.1-3.3) | ||||||
| CC | 2 | 5.6 (0.8-38.9) | 3 | 2.2 (0.4-11.4) | ||||||
| Acoustic neuroma | ||||||||||
| CASP8 (rs1045485) | GG | 18 | 1.0 (reference) | 26 | 1.0 (reference) | |||||
| GC | 5 | 0.8 (0.3-2.2) | 14 | 2.1 (1.0-4.4) | ||||||
| CC | 0 | — | 3 | 8.0 (1.4-46.9) | ||||||
| CCNH (rs2266690) | TT | 10 | 1.0 (reference) | 22 | 1.0 (reference) | |||||
| CT | 11 | 2.1 (0.8-5.2) | 16 | 1.6 (0.8-3.3) | ||||||
| CC | 2 | 4.8 (0.8-30.5) | 2 | 1.8 (0.3-9.4) | ||||||