Table 4.

ORs and 95% CIs for the association between common CASP8 haplotypes and risk of glioma, meningioma and acoustic neuroma, NCI adult brain tumor study, 1994 to 1998

Haplotype*Glioma (n = 354)
Meningioma (n = 133)
Acoustic neuroma (n = 66)
Controls (n = 495)
%OR%OR%OR%
G-A0.441.0 (reference)0.391.0 (reference)0.461.0 (reference)0.46
G-T0.421.0 (0.8-1.3)0.441.3 (0.9-1.7)0.350.8 (0.5-1.3)0.42
C-T0.141.1 (0.8-1.5)0.171.7 (1.1-2.6)0.191.5 (0.9-2.5)0.12
Global test omnibus0.670.0480.07
  • * Order of SNPs is CASP8 Ex13+51G>C and CASP8 Ex14-271A>T.

  • ORs and global test are adjusted for age and sex. Analyses restricted to non-Hispanic Whites.