Table 4.

ORs and 95% CIs for the association between common CASP8 haplotypes and risk of glioma, meningioma and acoustic neuroma, NCI adult brain tumor study, 1994 to 1998

Haplotype*	Glioma (n = 354)			Meningioma (n = 133)			Acoustic neuroma (n = 66)
Haplotype*		%	OR^†	%	OR	%	OR	%
G-A	0.44	1.0 (reference)	0.39	1.0 (reference)	0.46	1.0 (reference)	0.46
G-T	0.42	1.0 (0.8-1.3)	0.44	1.3 (0.9-1.7)	0.35	0.8 (0.5-1.3)	0.42
C-T	0.14	1.1 (0.8-1.5)	0.17	1.7 (1.1-2.6)	0.19	1.5 (0.9-2.5)	0.12
Global test omnibus		0.67		0.048		0.07

↵* Order of SNPs is CASP8 Ex13+51G>C and CASP8 Ex14-271A>T.
↵† ORs and global test are adjusted for age and sex. Analyses restricted to non-Hispanic Whites.